Gliomas are highly malignant intracranial tumors that result in a low survival rate due to an invasive phenotype and its diffuse nature. As a result, tumorigenic stem-like glioma cells are poorly targeted by conventional therapies. MAPK kinase 3 (MKK3) has been found to be a key upstream activator of the p38 MAPK protein and is upregulated in invasive glioma cells. Recent evidence suggests that interfering with MKK3 signaling through the inhibition of p38 can inhibit tumor cell invasion in vitro (Demuth et al. 2007). We are interested in examining the role of p38 in glioma through the ability of these cells to form tumor-like colonies in soft agar with modifications in Lgl1 gene expression

We will be conducting a musical event held locally at Blondie's in Arcata that incorporates a canned food drive and an assortment of raffle prizes. One of our goals is to support local businesses and to show the community how much they give back to HSU by asking these local businesses for donations for our raffle. We wish to accomplish entertainment that is in a safe and including environment. We also hope to create opportunities for OhSnap to provide more food for students. To not only be able to give back to the HSU students in need, but to also bring attention to the community that a program like OhSnap exists. We will donate all of our canned goods back to the OhSnap program.

A sensitive flow injection (FI) system for determining dissolved iron concentrations involved a complex manifold: peristaltic pump, two electronically actuated 6-port, 2-postion injection valves, UV-Vis spectrophotometer and a desktop computer controlled by a software program for data acquisition. The FI method allows for direct preconcentration of iron in samples at trace metal nanomolar concentrations using the catalytic colorimetric indicator N, N-dimethyl-p-phenylenediamine dihydrochloride. Toyopearl AF-Chelate-650M chelating resin is used to remove the need for sample treatments before preconcentrating and eliminate interferences from iron binding to organic ligands in the sample matrix

The suicide rate for young Indigenous men is 2x-4x higher than for other demographic groups. Causes include cultural disruption, historical trauma, grief, and health and social inequities. Prevention of self-harm is a core responsibility of healthcare. A rural clinic serving Indigenous people will implement a Zero Suicide Framework with input from local tribal members. Community members will help develop risk assessments, quality of life surveys, and the facilitation of participation in traditional cultural activities. This will protect by strengthening of belonging, connection, strong spirituality and physical health, and relationship within the community and with the natural world.

This study is intended to investigate food insecurity among international students, who are working on campus, and to provide greater understanding of the barriers for them and/or their families in accessing SNAP benefits. Twelve individuals who had experience working on campus 20 hours per week as an international student were recruited. A survey based on demographic and financial information and interviews were conducted to identify their financial situation and barriers to access SNAP benefits. The study identified that without the financial support of parents, international students with children face the risk of food insecurity.

Mismanagement of coral reef habitats for construction has impacted on rapid destruction of most biodiverse coral reefs of South Chinese sea. This project examines how coral reef habitats changed in Duncan island of South Chinese sea using object based image analysis (OBIA) and coral index. We estimated the coral changes over time with different land-use classes. The unchanged coral acreage was 7.80 acres between 2016-2017, 1.21 acres between 2017-2018 and 8.22 acres between 2016-2018. The coefficient of agreement for the classification is ranged from 0.55 to 0.60. NDCI Analysis of coral regions surrounding Duncan island revealed vegetation change in coral health.

The Helena fire occured August 30th– November 15th as a consequence of a power line contacting a tree limb on Bureau of Land Management public lands and spread to Trinity Alps Wilderness and Weaverville in Trinity County, California. This study examines before and after effects of this devastating fire using the Burn Index (BI) and Normalized Difference Vegetation Index (NDVI) using Landsat 8 images and ENVI and ArcGIS software. Burn severity acreage was calculated within fire State Responsibility Areas (SAR) and the results summarized using high, moderate and very high burn categories. The BI showed a 61% area effected by wildfire resulting in a 53% NDVI decrease within Helena fire SAR.

When aspects of culture and diversity are integrated into courses, students can benefit in many ways including enhanced critical thinking and greater social agency, or one’s belief in the importance of working to correct social injustice. Despite these benefits, few instructors report that they integrate diversity-related content into their course curriculum, with many citing lack of knowledge for how to do this as a primary barrier. The purpose of this study is to assess student perceptions of diversity in the curriculum using both quantitative and qualitative methodology, with the broader goal of informing future curriculum design.

We inventoried the epiphyte community in one 87 m tall Sitka spruce (Picea sitchensis) tree in the Redwood Experimental Forest north of Klamath, CA. For our inventory, we sampled approximately 5% of trunk, segment, branch, and branchlet area and found over 50 species of epiphytes. Functional groups of these epiphytes include microlichens, macrolichens, leafy liverworts, mosses, and ferns. For all epiphyte samples we estimated percent cover for spatial analyses of within-crown epiphyte distribution relative to crown height and distance from the bole. In this project we showcase some of the impressive biological diversity and introduce viewers to a variety of lesser-known botanical species.

Anabaena sensory rhodopsin (ASR) is a light-sensitive transmembrane protein found in the cyanobacterium Anabaena Nostoc. Membrane proteins have proven difficult to study due to their insolubility and tendency to form aggregates in aqueous environments. Nanodiscs are small protein structures that assist in the study of insoluble proteins. In this experiment, self-assembled ASR-bound nanodiscs were purified by Ni-NTA Immobilized Metal Affinity Chromatography (IMAC). Native gel electrophoresis, SDS-PAGE, western blotting, and absorption spectroscopy were used to detect Anabaena sensory rhodopsin and the scaffolding protein, ApoAI, in the prepared nanodisc sample.