Between set rest intervals (RI) are one of the most important variables in resistance training; however, no known research has investigated the effects of RIs greater than 5-min during strength training. The purpose of this research was to examine the effects of three different RIs on training volume (TV) completed during a high-intensity bench press exercise. 15 resistance trained males completed 3 experimental sessions, during which 4 sets of the bench press were performed. Resistance trained males, with the goal of greater volume during strength training, would benefit from longer RIs. Specifically, using an 8-min RI between 4 consecutive sets of a bench press allows for a greater TV.

Lethal (2) giant larvae 1 (Lgl1) maintains cell polarity and regulates cell migration. Its dysregulation is linked to gliomas, suggesting a role in tumor development. Glioblastomas may originate from neural stem/progenitor cells (NSPCs) accumulating mutations. Loss of Lgl1 in NPCs leads to cancer-like traits, including increased migration and altered signaling. Scanning electron microscopy can reveal morphological changes. This study compares WT and Lgl1 KO murine brain tissue, aiming to uncover changes associated with Lgl1 loss, offering insights into gliomagenesis.

This research represents the preliminary results of a longer term project in Sequoia National Park, California. I used temperature dataloggers to investigate western pond turtle behavior to better understand their natural history and thus inform monitoring protocol and conservation. These data suggest that snorkel surveys used to monitor turtle populations may be more effective if conducted at night. In addition, these data indicate the potential for intraspecific niche partitioning among turtles according to age. These early results hint at unique turtle behavior that is otherwise difficult to observe for a cryptic species and thereby warrant further investigation.

Currently food crops are used to produce bioethanol production, while plant waste cellulose could be used. However, cellulase enzymes are a limiting factor. We sought to characterize a novel cellulase identified by metagenomic analysis of bovine rumen by the JGI and Hess et al. We performed protein expression, genomic analysis, and characterization by SDS-PAGE, CMC and DNS activity assays, and electron microscopy of cellulose degradation. Our data indicates the cellulase is an endoglucanase with an activity of 6.27 cm2/ug, or 6x higher than commercial cellulase enzymes. These results have implications for creating efficient biofuels from agricultural waste products versus the current methods

The Ironside Mountain Batholith located in the Western Hayfork terrane in the Klamath Mountains province represents crustal derived plutonism that pre-dates the Nevadan Orogeny by 20Ma. Redating the Ironside Mountain Batholith will be done via U-Pb laser ablation of accessory zircons, this will yield an age of crystallization thus providing an age of emplacement, and constrain the pre-Nevadan orogeny. Barnes and Petersen dated the Ironside Mountain Batholith in 1992 using U-Pb, Pb-Pb, and K-Ar dating methods, and yielded a date in the Mid Jurassic from 169 Ma (K-Ar) to 174 Ma (U-Pb), with an accepted age of 170Ma.

The Western Snowy Plover is threatened by habitat loss from invasive European Beachgrass. Habitat restoration is implemented to counteract this threat. A second threat to this beach-nesting bird is flooding from sea level rise due to global warming. To inform managers, we evaluated these threats using GIS geospatial analyses to compare nesting habitat features in restored areas and evaluate sea level inundation. In this preliminary study, we found plovers nested on wider beaches with more woody debris, open sand, and other nests than at random. Most nests (84%) were in restored habitat, and a two meter increase from mean sea level would result in 53% of plover nests becoming inundated.

Many neurodegenerative diseases are characterized as cholesterol metabolism or storage disorders. Recently, the drug Efavirenz was implicated as a mediator of cholesterol-induced pathology in AD SC- based models. It restores function of MAP, tau, by mitigating cholesterol’s disruption of the UPS, which facilitates tau proteostasis. In this study, we are investigating the mechanistic target of cholesterol leading to UPS dysfunction. We are using human SC-derived neurons to model UPS dysfunction at different regulatory levels and determine which stages can be rescued with Efavirenz treatment. We will use this drug to aid in the complete characterization of cholesterol-mediated tauopathy.

Our project is focused on developing educational materials on energy efficiency targeted to renters and student residence hall occupants. We are developing a checklist of possible actions that will include building energy efficiency, appliances, transportation, and energy purchasing options that are available to typical renters, who do not have the ability to make major improvements to their home. The main outcome will be a set of appropriate outreach materials to help deliver these messages. We will develop draft materials, workshop these with current renters, and improve the messages based on their feedback. The goal is to empower renters to make positive clean energy choices.

We found that not only did participants experiencing high self-uncertainty make fewer overall errors, but more interestingly, they demonstrated greater accuracy for self-relevant word-pairings than those low in uncertainty. This in turn affected reaction times pairing self-relevant vs. self-irrelevant words. This implies that uncertainty might not lead to cognitive load or distracted and heuristic processing. Instead, we suggest that uncertainty can create a motivated process with respect to self-relevant information, leading to more accurate judgments about the self, perhaps in an attempt to reduce uncertainty.

A new one-dimensional ocean wave model was derived and applied to the Humboldt Bay Channel. This model consists of the continuity equation and momentum equation which describe the incomprehensibility and movement of sea water. This model was digitized on a computer using the Octave programming language and simulations were ran for five different ocean swell scenarios. Wind generated this swell ranging in speed from 10 to 50 nautical miles per hour, yielding wavelengths in the range of 8.5 to 212 meters with wave speeds in the range of 2.8-14.8 meters/second. In all cases the measured speeds agreed the the theoretical shallow water wave speed.