The mitochondrion is a subcellular location for varied metabolic processes and pathways relevant to undergraduate biochemistry courses at Cal Poly Humboldt. At the core of such pathways are integral membrane proteins (IMPs) whose structure and enzymatic activity can be examined to better understand not only their overall function, but also the role of specific subunits. One such enzyme is cytochrome c oxidase (complex IV). Nanodiscs are invaluable tools for examining IMPs. In this experiment, we isolated mitochondria and submitochondrial particles for incorporation into nanodiscs. Future work will include purification and selection for nanodiscs containing only cytochrome c oxidase.

Meet and Eat was a project created to educate high school students from the grade tenth to twelfth. Workshops were created to educate students about what options they have post graduation. Examples consisted of helping students understand how to apply for FASFA, job resources available to students, and learning about resources on college campuses as well as learning about the benefits of a 2 year and 4 year college. This project took place in Del Norte County’s school District and was open to students within the McKinney Vento and Foster Youth program.

This special issue of the Humboldt Journal of Social Relations (HJSR) captures work and experiences in higher education as they relate to changes and challenges around diversifying U.S. college campuses. Race, class, gender, sexuality, able-bodiedness, and citizenship shape contemporary conversations about campus climate, curricular content, organizational structures, decision making and the disparate impacts of related policy changes or stagnation. These conversations shape the everyday experiences of faculty and staff, and ultimately are linked to student success.

Anthropologists use Stable isotope analyses to understand environments where past and present human cultures lived. This project starts a database of isotopic signatures for the region of Humboldt County, in northwestern California, as a baseline for further research. I prepared samples at HSU Archaeology and Biological Anthropology Research labs for Carbon (C) and Oxygen (O) stable isotopes using H2O2 Hydroxyapatite-Carbonate protocol. The samples will be sent to Stable Isotope Laboratory at the University of California, Santa Cruz and analyzed for δ13C & δ18O. As database entries increase, evidence of stable isotopic signatures of specific areas in northwest California may be identified.

We wish to answer whether or not nanodiscs make an effective means of transporting medication, specifically in the treatment of fungal infections, seeing as research is currently examining its effectiveness in the transport of chemotherapy drugs to prevent collateral cell death. We tested nanodisc transport of the antifungal terbinafine, which is often used as a topical ointment for direct application, to determine if naondiscs improve its effectiveness as a fungal killer. We treated cultured samples of Brewer's yeast (Saccharomyces cerevisiae) with DMPC lipid nanodiscs wrapped in Apo-A1 protein and loaded with terbinafine and observed fungal cell death, as compared to direct application.

Rapid Response Teams are a resource for hospitals to provide early and emergent interventions to prevent the need for escalation of care. Team members can be called upon by units in the hospital for consultation and assist with assessments. Teams provide a proactive rounding process on patients with high-risk diagnoses to follow along with the bedside nurse to provide an interdisciplinary approach to a complex patient. Rural hospitals are challenged with retaining highly experienced nurses, these teams provide insight and mentorship to newer nurses.

The current state of policing in the United States is a heavily politicized issue. In response to instances of excessive police force on vulnerable populations, civilian law enforcement review boards (CLERBs) were developed to improve accountability. In this study, we investigated support for CLERBs and attitudes toward law enforcement in Humboldt County. Drawing from the social identity theory framework and intergroup contact theory, our work shows that people’s beliefs about how marginalized communities are treated by law enforcement predicts their attitudes toward law enforcement, and this in turn predicts support for CLERBs. We discuss these relationships and their implications.

This project delves into the role of College Corps in fostering community engagement and leadership development in climate action. Through collaborative partnerships with local nonprofit organizations, College Corps provides students with opportunities to address pressing social environmental challenges while deepening their connections within the community. This case study follows my journey as a College Corps fellow who, driven by a passion for environmental and social justice, has made significant contributions in waste reduction and community garden initiatives. My experiences illustrate the programs’ efficacy in empowering students to become catalysts for change.

The review overviews the prevalence, characteristics, risk factors, and possible treatment of transgender persons with MD symptomatology. Little is known about the prevalence and presentation of MD among gender minorities and far fewer is known on how to treat MD.

I will be describing research done by the Native Medicinal Plant Research Program relating to ethnobotany. The research includes: their botany database, plants collected, Physalis research, osha, at risk plants, asclepius, and echinacea. The core values of this research are Conservation and sustainable harvest of medicinal plants , Respect for Indigenous knowledge of medicinal plants , and Education toward ecological responsibility,